منابع مشابه
NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES
Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and an...
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play novel properties as materials. Although there are a variety of methods known for the preparation of sulfones, the majority of these processes feature associated limitations. For example, oxidation of the corresponding sulfide relies on functional-group compatibility with oxidizing agents and the availability of catalysts to promote selectivity for sulfone formation over sulfoxide formation...
متن کاملgem-Difluoroolefination of diaryl ketones and enolizable aldehydes with difluoromethyl 2-pyridyl sulfone: new insights into the Julia-Kocienski reaction.
The direct conversion of diaryl ketones and enolizable aliphatic aldehydes into gem-difluoroalkenes has been a long-standing challenge in organofluorine chemistry. Herein, we report efficient strategies to tackle this problem by using difluoromethyl 2-pyridyl sulfone as a general gem-difluoroolefination reagent. The gem-difluoroolefination of diaryl ketones proceeds by acid-promoted Smiles rear...
متن کاملnitroimidazoles viii [i]. syntheses, antibacterial and antifungal activities of 2-pyridyl-nitroimidazoles
starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. from the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. reaction of compound 15 with diazomethane gave i-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. the antibacterial and antif...
متن کاملThe polysulfonylamines bis(methylsulfonamido) sulfone and bis(trifluoromethylsulfonamido) sulfone.
Bis(methylsulfonamido) sulfone, C(2)H(8)N(2)O(6)S(3) or SO(2)(NHSO(2)CH(3))(2), was synthesized from imidobis(sulfonyl chloride), HN(SO(2)Cl)(2), and bis(trimethylsilyl)methane, CH(2)[Si(CH(3))(3)](2), in chlorotrimethylsilane solution. In the solid state, there are two independent molecules linked by two N-H...O hydrogen bridges into infinite chains parallel to the b axis. The central S atoms ...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1961
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.81.12_1812